Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

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Fludrocortisone Is Associated With a Higher Risk of All‐Cause Hospitalizations Compared With Midodrine in Patients With Orthostatic Hypotension

BACKGROUND Orthostatic hypotension causes ≈80 000 hospitalizations per year in the United States. Treatments for orthostatic hypotension include fludrocortisone, a mineralocorticoid analog that promotes sodium reabsorption; and midodrine, an α-1 adrenergic agonist that is a direct vasoconstrictor. Although both medications are used to treat orthostatic hypotension, few studies have compared the...

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Is there a risk of orthostatic hypotension associated with antihypertensive therapy in geriatric inpatients?

Objectives: To determine the risk of orthostatic hypotension (OH) due to antihypertensive therapy in a geriatric inpatient population. Subjects and methods: This observational cohort study included 388 patients (mean age 80.7, 68.5% female) hospitalized in a geriatric clinic. OH risk was evaluated by orthostatic testing (OT), with manual measurement of blood pressure after 30 minutes supine (T0...

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ژورنال

عنوان ژورنال: Journal of the American Heart Association

سال: 2017

ISSN: 2047-9980,2047-9980

DOI: 10.1161/jaha.117.006848